Abstract: The signing of the first phase of China-US economic and trade agreement means that Sino-US economic and trade frictions have shown signs of easing temporarily, indicating that as long as the attitude and spirit of equality and mutual respect are upheld, the economic and trade differences between China and the United States can be resolved through dialogue and consultation. From the perspective of the true strategic intentions and essential causes of the United States to initiate economic and trade frictions with China, the long-term, complex and volatile nature of Sino-US economic and trade frictions will not change. Therefore, on the one hand, we should discard the illusion that the trade frictions between China and the United States can be resolved in a short period of time; on the other hand, we should focus on the future and deal with the frictions calmly. The core and key short-term response measures are as follows: responding quickly and effectively according to the specific measures taken by the United States to initiate economic and trade frictions, fighting without breaking; treating the United States with constant contact, trial, negotiation, etc. to prevent the decoupling of China and the United States; and minimizing the negative impact as much as possible, so as to gain time for China to further open up and create an external environment as favorable as possible. The core and key long-term response measures contain maintaining strategic focus, rethinking the national strategy of trade and realizing the strategic transformation as soon as possible, enhancing the ability to participate in and govern economic globalization, and eventually forming a benign competitive relationship with the United States.