Abstract: The Coronavirus Disease 2019 (COVID-19) is still raging,which has caused a huge psychological impact on people.Based on the characteristics of psychological stress and assistance under epidemic circumstances,this paper puts forward an intervention strategy which takes help seekers as the center,focuses on the goal,and questions in an integrated way with orientations of evaluation,empathy and positive resources.Through the analysis of four psychological assistance cases,the effective intervention strategy was further interpreted.