Abstract: Cultural responsibility is the inherent stipulation of the property of cultural industry. The cultural responsibility of cultural industry includes the unity of cultural satisfaction responsibility and cultural leading responsibility, the unity of cultural inheritance responsibility and cultural innovation responsibility, and the unity of domestic cultural responsibility and international cultural responsibility. In the new era, cultural construction puts forward higher requirements for cultural responsibility to the cultural industry, emphasizing the value orientation, aesthetic function and safety responsibility of the cultural industry. In order to realize the cultural responsibility given to cultural industry in the new era, we must strengthen the construction of cultural industry, and strive to find a way to develop the socialist cultural industry with Chinese characteristics. Firstly, we should improve our political position and strengthen our responsibility; secondly, we should adhere to cultural consciousness and correct orientation; thirdly, we should adhere to the "people's center" and create cultural classics; fourthly, we should adhere to Chinese culture and strengthen international exchanges; fifthly, we should improve the institutional mechanism and accept social supervision.